Necrotizing enterocolitis (NEC) is a devastating disease that occurs in 1 out of 10 early preterm infants and the rate of death is close to 30%. Survivors are at risk for short-bowel syndrome (caused by surgical removal of the small intestine) and neurodevelopmental disability.
Researchers at the Cincinnati Children’s Hospital Medical Center have found a new biomarker with predictive value for NEC above 80%.
“Early microbial and metabolomic signatures predict later onset of necrotizing enterocolitis in preterm infants”, Ardythe L Morrow, Anne J Lagomarcino, Kurt R Schibler, Diana H Taft, Zhuoteng Yu, Bo Wang, Mekibib Altaye, Michael Wagner, Dirk Gevers, Doyle V Ward, Michael A Kennedy, Curtis Huttenhower and David S Newburg is published in Microbiome Journal.
Updated: